ICH ICH Enumeration: ShortName=ICH M11 Section Amendment Details Terminology

M2 ESTRI Code List

ShortName = ICH M11 Section Amendment Details Terminology
LongName = ICH M11 Section Amendment Details Terminology
Version = 1.0
CanonicalUri = 2.16.840.1.113883.3.989.2.3.3.15
CanonicalVersionUri = 2.16.840.1.113883.3.989.2.3.3.15.1
Agency
ShortName = M11
LongName = Clinical Trial protocols
Identifier = C217357
code
Id="code"
(required)
Type="string"
english-label
Id="en"
(optional)
Type="string" Lang="en"
M11 Definition
Id="en_def"
(optional)
Type="string" Lang="en"
current flag
Id="cf"
(optional)
Type="string" Lang="en"
C218694 Amendment Details A written message within the study protocol that describes the amendment details, especially as to whether the protocol has been amended previously. y
C218695 Amendment Scope Enrollment Description The enrollment description as to whether the amendment scope applies globally, locally, or per cohort across the trial. y
C42581 Amendment Summary A short description describing the changes introduced in the current version of the protocol. y
C218478 Approximately <#/%> enrolled The value (expressed either numerically or as a percentage) for the estimated number of participants enrolled at the time of the protocol amendment. y
C181233 Brief Rationale for Change The brief reason for the change introduced in the current or prior version of the protocol. y
C218701 Briefly Explain Substantial Impact on Data A short descriptive account of any substantial impacts on the reliability and robustness of the data generated in the clinical trial due to the protocol amendment. y
C218699 Briefly Explain Substantial Impact On Safety A short descriptive account of any substantial impacts on the safety or rights of the participants due to the protocol amendment. y
C218483 Description of Change A description of the change introduced in the current or prior version of the protocol. y
C218700 Is this amendment likely to have a substantial impact on the reliability and robustness of the data generated in the clinical trial? An indication as to whether the amendment likely to have a substantial impact on the reliability and robustness of the data generated in the clinical trial. y
C218698 Is this amendment likely to have a substantial impact on the safety or rights of the participants? An indication as to whether the amendment is likely to have a substantial impact on the safety or rights of the participants. y
C218696 Primary Reason for Amendment The rationale of greatest importance for the protocol amendment. y
C218697 Secondary Reason for Amendment Additional rationale for the protocol amendment that is not considered the primary rationale. y
C218479 Section # and Name The protocol section number and name containing the change introduced in the current or prior version of the protocol. y

This file contains a code list co-maintained by ICH M2 ESTRI and CDISC in collaboration with the NCI Enterprise Vocabulary Services (EVS). It is encoded using OASIS genericode. More information on ICH technical standards is available via the M2 ESTRI webpages at www.ich.org.

Change History: v1.0 (November 11 2025)

Report created by ICH_M2_CDISC_Codelist.xsl : [Revision: 1.1 ] : ICH : Harmonisation for Better Health